Magnetic resonance imaging of ultrasmall superparamagnetic iron oxide-labeled exosomes from stem cells: a new method to obtain labeled exosomes

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Magnetic resonance imaging of ultrasmall superparamagnetic iron oxide-labeled exosomes from stem cells: a new method to obtain labeled exosomes

PURPOSE Recent findings indicate that the beneficial effects of adipose stem cells (ASCs), reported in several neurodegenerative experimental models, could be due to their paracrine activity mediated by the release of exosomes. The aim of this study was the development and validation of an innovative exosome-labeling protocol that allows to visualize them with magnetic resonance imaging (MRI). ...

متن کامل

Magnetic resonance imaging of transplanted mouse islets labeled with chitosan-coated superparamagnetic iron oxide nanoparticles.

Although only 10% of islet recipients maintain insulin independence, 80% of them are C-peptide positive at 5 years after transplantation. To better understand the fate of transplanted islets, a magnetic resonance imaging (MRI) technique has been used to detect Feridex-labeled islet grafts in rodents. In this study, we used a novel MRI contrast agent, chitosan-coated superparamagnetic iron oxide...

متن کامل

Magnetic Resonance Imaging of Mouse Islet Grafts Labeled with Novel Chitosan-Coated Superparamagnetic Iron Oxide Nanoparticles

OBJECT To better understand the fate of islet isografts and allografts, we utilized a magnetic resonance (MR) imaging technique to monitor mouse islets labeled with a novel MR contrast agent, chitosan-coated superparamagnetic iron oxide (CSPIO) nanoparticles. MATERIALS AND METHODS After being incubated with and without CSPIO (10 µg/ml), C57BL/6 mouse islets were examined under transmission el...

متن کامل

sensitivity of susceptibility-weighted imaging in detecting superparamagnetic iron oxide-labeled mesenchymal stem cells: a comparative study

background susceptibility-weighted imaging (swi) is extremely sensitive in the detection of superparamagnetic iron oxide (spio) nanoparticle-labeled cells. however, no study has compared molecular imaging for stem cell detection using swi and other mri pulse sequences. objectives this study aims to assess the sensitivity of swi in detecting spio nanoparticle-labeled, human bone marrow-derived m...

متن کامل

magnetic resonance imaging of human-derived amniotic membrane stem cells using pegylated superparamagnetic iron oxide nanoparticles

objective: the label and detection of cells injected into target tissues is an area of focus for researchers. iron oxide nanoparticles can be used to label cells as they have special characteristics. the purpose of this study is to examine the effects of iron oxide nanoparticles on human-derived amniotic membrane stem cell (hamcs) survival and to investigate the magnetic properties of these nan...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: International Journal of Nanomedicine

سال: 2016

ISSN: 1178-2013

DOI: 10.2147/ijn.s104152